Resistance of Staphylococcus aureus to sulphamethoxazole and trimethoprim
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چکیده
منابع مشابه
Resistance of Staphylococcus aureus to sulphamethoxazole and trimethoprim.
Strains of Staphylococcus aureus isolated from the lesions of hospital patients were surveyed for resistance to sulphamethoxazole and to trimethoprim. Of 675 strains tested, 18.5% were resistant to sulphamethoxazole and 1.6% to trimethoprim. All the trimethoprim-resistant strains were resistant to sulphamethoxazole and to a 1:20 mixture of the two drugs. Trimethoprim-resistant strains were on a...
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Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens. One hundred and nine patients with genital ulcers (75 men and 34 women) seen at the Special Treatment Clinic in Nairobi, Kenya, were randomly assigned to treatment with a seven day course of either s...
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OBJECTIVES This study sought to expand knowledge on the molecular mechanisms of mutational resistance to trimethoprim in Staphylococcus aureus, and the fitness costs associated with resistance. METHODS Spontaneous trimethoprim-resistant mutants of S. aureus SH1000 were recovered in vitro, resistance genotypes characterized by DNA sequencing of the gene encoding the drug target (dfrA) and the ...
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When tested on Wellcotest (sensitivity test agar, Wellcome) supplemented with lysed horse blood, 59 clinical isolates of beta-haemolytic streptococci, belonging to several serological groups, are all sensitive to sulphamethoxazole, to trimethoprim, and to cotrimoxazole. The results obtained on diagnostic sensitivity test agar (Oxoid) containing lysed horse blood are comparable. When Mueller Hin...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1972
ISSN: 0021-9746
DOI: 10.1136/jcp.25.8.708